HGH (Human Growth Hormone)
Also known as: Human Growth Hormone, somatotropin
HGH is a 191-amino-acid protein hormone produced by the pituitary gland that drives growth and metabolism. While technically a protein rather than a peptide, it is central context for GHRH and GHRP research peptides; it is dosed in International Units (1 IU ≈ 333 mcg).
Overview
Human Growth Hormone (somatotropin) is secreted in pulses from the anterior pituitary, primarily during sleep and in response to exercise, fasting, and stress. Its anabolic and metabolic effects are largely mediated through IGF-1 produced by the liver. HGH levels decline with age — a phenomenon sometimes called somatopause — which underlies research interest in GHRH and GHRP peptides that stimulate endogenous HGH production without requiring exogenous HGH administration. Recombinant HGH (somatropin) is FDA-approved for specific deficiency conditions. In research contexts, HGH is dosed in International Units where 1 IU ≈ 333 mcg (or 1 mg ≈ 3 IU). The IU conversion calculator is helpful when comparing protocols that mix IU and mcg dosing conventions.
Related Terms
Related Calculators
Frequently asked questions
Is HGH a peptide or a protein?+
At 191 amino acids, HGH is technically a protein. However, it is commonly discussed alongside research peptides because GHRH and GHRP peptides stimulate its endogenous release.
How do you convert HGH IU to mg?+
Divide IU by 3 to get mg (or multiply mg by 3 to get IU). 1 mg HGH ≈ 3 IU; 2 IU HGH ≈ 0.67 mg = 667 mcg.
What is the difference between exogenous HGH and GHRH/GHRP peptides?+
Exogenous HGH directly supplies the hormone. GHRH and GHRP peptides instead stimulate the pituitary to produce HGH naturally, preserving the pulsatile secretion pattern and potentially avoiding the pituitary suppression associated with chronic exogenous HGH administration.