TB-500 (Thymosin Beta-4 Fragment)
Also known as: TB500, Thymosin Beta-4 Fragment
TB-500 is a 43-amino-acid synthetic fragment of Thymosin Beta-4, a naturally occurring protein involved in cell migration, angiogenesis, and tissue repair. It is studied as a systemic tissue repair research peptide.
Overview
Thymosin Beta-4 is a 43-amino-acid protein ubiquitously expressed in mammalian tissues, where it sequesters actin monomers and regulates cell motility and differentiation. TB-500 refers to the synthetic version of this full-length protein (some sources distinguish the specific LKKTETQ motif fragment, though 'TB-500' in the research market typically refers to the full 43-AA sequence). Research interest centers on its potential to promote angiogenesis (new blood vessel formation), reduce inflammation, and accelerate healing of various tissue types. TB-500 is frequently stacked with BPC-157 in research protocols because the two peptides are proposed to complement each other through different repair mechanisms: BPC-157 targeting local signaling and TB-500 promoting systemic cell migration.
Related Terms
Related Peptide Profiles
Frequently asked questions
Is TB-500 the same as Thymosin Beta-4?+
TB-500 in the research market is generally the synthetic version of the full 43-amino-acid Thymosin Beta-4 sequence, though the names are sometimes used interchangeably or refer to slightly different fragments.
Why is TB-500 often stacked with BPC-157?+
BPC-157 is studied for its effects on local tissue signaling and gastroprotection, while TB-500 is studied for promoting cell migration and systemic angiogenesis — complementary mechanisms that researchers hypothesize may be synergistic.
How is TB-500 administered in research?+
TB-500 is typically administered via subcutaneous injection in animal and human research contexts. Due to its larger size (43 amino acids), oral administration is not expected to be effective.